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Quantification of desloratadine in human plasma by LC-ESI-MS/MS and application to a pharmacokinetic study

A simple, sensitive, and specific liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the quantification of desloratadine (DL) in human plasma using desloratadine-d5 (DLD5) as an internal standard (IS). Chromatographic separation was performed using an Xbridge C18 colu...

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Detalles Bibliográficos
Autores principales: Ponnuru, Venkata Suresh, Challa, B.R., Nadendla, Ramarao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760887/
https://www.ncbi.nlm.nih.gov/pubmed/29403740
http://dx.doi.org/10.1016/j.jpha.2012.01.008