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Simultaneous determination of pioglitazone and candesartan in human plasma by LC-MS/MS and its application to a human pharmacokinetic study

A simple and rapid liquid chromatography-tandem mass spectrometric (LC-MS/MS) assay method has been developed and fully validated for simultaneous quantification of pioglitazone and candesartan in human plasma. Irbesartan was used as an internal standard. The analytes were extracted from human plasm...

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Detalles Bibliográficos
Autores principales: Kumari Karra, Vijaya, Rao Pilli, Nageswara, Kumar Inamadugu, Jaswanth, Seshagiri Rao, J.V.L.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760890/
https://www.ncbi.nlm.nih.gov/pubmed/29403738
http://dx.doi.org/10.1016/j.jpha.2012.01.002