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Analysis of species-dependent hydrolysis and protein binding of esmolol enantiomers

The stereoselective hydrolysis of esmolol in whole blood and in its separated components from rat, rabbit and human was investigated. Blood esterase activities were variable in different species in the order of rat>rabbit>human. Rat plasma showed the high esterase activity and had no stereosel...

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Detalles Bibliográficos
Autores principales: Tang, Yi-Hong, Wang, Jun-Yan, Hu, Hai-Hong, Yao, Tong-Wei, Zeng, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760893/
https://www.ncbi.nlm.nih.gov/pubmed/29403746
http://dx.doi.org/10.1016/j.jpha.2012.01.007