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Analysis of species-dependent hydrolysis and protein binding of esmolol enantiomers
The stereoselective hydrolysis of esmolol in whole blood and in its separated components from rat, rabbit and human was investigated. Blood esterase activities were variable in different species in the order of rat>rabbit>human. Rat plasma showed the high esterase activity and had no stereosel...
Autores principales: | Tang, Yi-Hong, Wang, Jun-Yan, Hu, Hai-Hong, Yao, Tong-Wei, Zeng, Su |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760893/ https://www.ncbi.nlm.nih.gov/pubmed/29403746 http://dx.doi.org/10.1016/j.jpha.2012.01.007 |
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