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Validated gradient stability indicating HPLC method for determining Diltiazem Hydrochloride and related substances in bulk drug and novel tablet formulation

A stability-indicating liquid chromatographic method has been developed and validated for the determination of Diltiazem Hydrochloride (DTZ) together with its six related substances (Diltiazem sulphoxide, Imp-A, Imp-B, Imp-D, Imp-E, and Imp-F) in a laboratory mixture as well as in a novel tablet for...

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Detalles Bibliográficos
Autores principales: Chatpalliwar, Vivekanand A., Porwal, Pawan K., Upmanyu, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760901/
https://www.ncbi.nlm.nih.gov/pubmed/29403747
http://dx.doi.org/10.1016/j.jpha.2012.01.003