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Simultaneous determination of atorvastatin, metformin and glimepiride in human plasma by LC–MS/MS and its application to a human pharmacokinetic study

A simple, rapid and sensitive liquid chromatography-tandem mass spectrometric (LC–MS/MS) assay method has been developed and fully validated for the simultaneous quantification of atorvastatin, metformin and glimepiride in human plasma. Carbamazepine was used as internal standard (IS). The analytes...

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Detalles Bibliográficos
Autores principales: Polagani, Srinivasa Rao, Pilli, Nageswara Rao, Gajula, Ramakrishna, Gandu, Venkateswarlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760920/
https://www.ncbi.nlm.nih.gov/pubmed/29403791
http://dx.doi.org/10.1016/j.jpha.2012.09.002