Kinetics study of metaxalone degradation under hydrolytic, oxidative and thermal stress conditions using stability-indicating HPLC method

An isocratic stability indicating RP-HPLC–UV method is presented for the determination of metaxalone (MET) in the presence of its degradation products. The method uses Dr. Maisch C18 column (250 mm×4.6 mm, 5 μm) with mobile phase consisting of acetonitrile–potassium dihydrogen orthophosphate buffer...

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Detalles Bibliográficos
Autores principales: Marothu, Vamsi Krishna, Dash, Rajendra N., Vemula, Saritha, Donkena, Shravani, Devi, Ramesh, Gorrepati, Madhavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760939/
https://www.ncbi.nlm.nih.gov/pubmed/29403778
http://dx.doi.org/10.1016/j.jpha.2012.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760939/
https://www.ncbi.nlm.nih.gov/pubmed/29403778
http://dx.doi.org/10.1016/j.jpha.2012.08.004

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