Cargando…

Kinetics study of metaxalone degradation under hydrolytic, oxidative and thermal stress conditions using stability-indicating HPLC method

An isocratic stability indicating RP-HPLC–UV method is presented for the determination of metaxalone (MET) in the presence of its degradation products. The method uses Dr. Maisch C18 column (250 mm×4.6 mm, 5 μm) with mobile phase consisting of acetonitrile–potassium dihydrogen orthophosphate buffer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marothu, Vamsi Krishna, Dash, Rajendra N., Vemula, Saritha, Donkena, Shravani, Devi, Ramesh, Gorrepati, Madhavi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760939/ https://www.ncbi.nlm.nih.gov/pubmed/29403778 http://dx.doi.org/10.1016/j.jpha.2012.08.004

Ejemplares similares

Method development and validation of HPLC tandem/mass spectrometry for quantification of perindopril arginine and amlodipine besylate combination in bulk and pharmaceutical formulations
por: Duraisamy, Kalaiyarasi, et al.
Publicado: (2017)

Assessment by HPLC of the degradation behavior of acitretin under hydrolytic, oxidative, photolytic and thermal stress conditions
por: Porwal, Pawan K., et al.
Publicado: (2014)

Metaxalone-induced Immune Hemolytic Anemia
por: Onyechi, Afoma, et al.
Publicado: (2023)

New Stability-Indicating RP-HPLC Method for Determination of Diclofenac Potassium and Metaxalone from their Combined Dosage Form
por: Panda, Sagar Suman, et al.
Publicado: (2012)

Isostructural cocrystals of metaxalone with improved dissolution characteristics
por: Gohel, Sunil Kumar, et al.
Publicado: (2021)

Hydrolytic Degradation Profile and RP-HPLC Estimation of Cilostazol in Tablet Dosage Form
por: Basniwal, P. K., et al.
Publicado: (2008)

Investigation of the Thermal and Hydrolytic Degradation of Polylactide during Autoclave Foaming
por: Dreier, Julia, et al.
Publicado: (2021)

Investigation of the Influence of PLA Molecular and Supramolecular Structure on the Kinetics of Thermal-Supported Hydrolytic Degradation of Wet Spinning Fibres
por: Giełdowska, Małgorzata, et al.
Publicado: (2020)

A solvent-free HPLC method for the simultaneous determination of Favipiravir and its hydrolytic degradation product
por: Sharaf, Yasmine Ahmed, et al.
Publicado: (2023)

Formulation, validation and evaluation studies on metaxalone and diclofenac potassium topical gel
por: Tiwari, Ashutosh, et al.
Publicado: (2021)

Demonstration of relative bioavailability of newly developed and innovator drug metaxalone 800 mg in healthy subjects under fed condition
por: Colaco, Socorrina, et al.
Publicado: (2022)

Development of a Stability-Indicating RP-UPLC Method for Rapid Determination of Metaxalone and its Degradation Products in Solid Oral Dosage Form
por: Trivedi, Rakshit Kanubhai, et al.
Publicado: (2012)

Influence of amorphous cellulose on mechanical, thermal, and hydrolytic degradation of poly(lactic acid) biocomposites
por: Wan Ishak, Wan Hafizi, et al.
Publicado: (2020)

MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
por: Pallio, Giovanni, et al.
Publicado: (2021)

Change in thermal transitions and water uptakes of poly(l-lactic acid) blends upon hydrolytic degradation
por: Oyama, Hideko T., et al.
Publicado: (2016)

Kinetic studies on Lewis acidic metal polyesterification catalysts – hydrolytic degradation is a key factor for catalytic performance
por: Wolzak, Lukas A., et al.
Publicado: (2022)

Polyethylene-Like Blends Amenable to Abiotic Hydrolytic Degradation
por: Eck, Marcel, et al.
Publicado: (2023)

Degradation Kinetics of Atorvastatin under Stress Conditions and Chemical Analysis by HPLC
por: Oliveira, Marcelo Antonio, et al.
Publicado: (2013)

Estimation of sertraline by chromatographic (HPLC-UV(273 nm)) technique under hydrolytic stress conditions
por: Rahman, Md. Akhlaquer, et al.
Publicado: (2012)

Synthesis and Hydrolytic Degradation of Substituted Poly(DL-Lactic Acid)s
por: Tsuji, Hideto, et al.
Publicado: (2011)

Structure–efficiency relationships of cyclodextrin scavengers in the hydrolytic degradation of organophosphorus compounds
por: Letort, Sophie, et al.
Publicado: (2017)

Quantitative analyses to estimate the bioaccessibility of a hydrolytically degradable cationic flocculant
por: Russell, Derek A., et al.
Publicado: (2021)

Impact of Glass Composition on Hydrolytic Degradation of Polylactide/Bioactive Glass Composites
por: Lyyra, Inari, et al.
Publicado: (2021)

Hydrolytic Degradation and Bioactivity of Electrospun PCL-Mg-NPs Fibrous Mats
por: Salaris, Valentina, et al.
Publicado: (2023)

Non-isothermal kinetics of thermal degradation of chitosan
por: Georgieva, Velyana, et al.
Publicado: (2012)

Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide
por: Fumagalli, Laura, et al.
Publicado: (2018)

The Hydrolytic Stability and Degradation Mechanism of a Hierarchically Porous Metal Alkylphosphonate Framework
por: Lv, Kai, et al.
Publicado: (2018)

RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
por: Sikorska, Natalia, et al.
Publicado: (2017)

Importance of Defluviitalea raffinosedens for Hydrolytic Biomass Degradation in Co-Culture with Hungateiclostridium thermocellum
por: Rettenmaier, Regina, et al.
Publicado: (2020)

The Influence of Polymer Composition on the Hydrolytic and Enzymatic Degradation of Polyesters and Their Block Copolymers with PDMAEMA
por: Kupczak, Maria, et al.
Publicado: (2021)

Changes in Crystal Structure and Accelerated Hydrolytic Degradation of Polylactic Acid in High Humidity
por: Kobayashi, Yutaka, et al.
Publicado: (2021)

Amino Acid-Based Polyphosphorodiamidates with Hydrolytically Labile Bonds for Degradation-Tuned Photopolymers
por: Haudum, Stephan, et al.
Publicado: (2023)

Effect of pH on the Hydrolytic Kinetics of Gamma-Glutamyl Transferase from Bacillus subtilis
por: Balakrishna, Sharath, et al.
Publicado: (2014)

Thermal Degradation Kinetics of ZnO/polyester Nanocomposites
por: Franco-Urquiza, E. A., et al.
Publicado: (2020)

Validating a Stability Indicating HPLC Method for Kinetic Study of Cetirizine Degradation in Acidic and Oxidative Conditions
por: Souri, Effat, et al.
Publicado: (2013)

Kinetic Study of the Alkaline Degradation of Oseltamivir Phosphate and Valacyclovir Hydrochloride using Validated Stability Indicating HPLC
por: Al-Bagary, Ramzia I, et al.
Publicado: (2014)

Study of Degradation Kinetics and Structural Analysis of Related Substances of Ceftobiprole by HPLC with UV and MS/MS Detection
por: Boczar, Dariusz, et al.
Publicado: (2022)

Hydrolytic Degradability, Cell Tolerance and On-Demand Antibacterial Effect of Electrospun Photodynamically Active Fibres
por: Contreras, Amy, et al.
Publicado: (2020)

Hydrolytic Degradation of Polylactic Acid Fibers as a Function of pH and Exposure Time
por: Vaid, Radhika, et al.
Publicado: (2021)

Hydrolytically Degradable PEG-Based Inverse Electron Demand Diels–Alder Click Hydrogels
por: Dimmitt, Nathan H., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_96dnrhaoe532nc0ns2ttjej53e