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LC–MS/MS assay for the determination of natamycin in rabbit and human plasma: Application to a pharmacokinetics and protein binding study

To enable reliable quantification of natamycin in rabbit and human plasma, a validated, sensitive and selective liquid chromatography–tandem mass spectrometry assay was developed. The chromatographic separation was achieved isocratically on a Cyano column using methanol: aqueous 3.5 mM ammonium acet...

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Detalles Bibliográficos
Autores principales: Chhonker, Yashpal Singh, Kumar, Devendra, Shrivastava, Pankaj, Kumar, Deepak, Singh, Rajbir, Chandasana, Hardik, Bhatta, Rabi Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760952/
https://www.ncbi.nlm.nih.gov/pubmed/29403809
http://dx.doi.org/10.1016/j.jpha.2012.11.003