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Simultaneous pharmacokinetic assessment of cefadroxil and clavulanic acid in human plasma by LC–MS and its application to bioequivalence studies

A simple, rapid and selective liquid chromatography–atmospheric pressure chemical ionization–mass spectrometry (LC–APCI–MS) assay method has been developed and fully validated for the simultaneous quantification of cefadroxil (CF) and clavulanic acid (CA) in human plasma. Analytes and internal stand...

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Detalles Bibliográficos
Autores principales: Nagarajan, Janaki Sankarachari Krishnan, Vimal, Chandran Sathish, George, Renjith, Dubala, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760965/
https://www.ncbi.nlm.nih.gov/pubmed/29403829
http://dx.doi.org/10.1016/j.jpha.2013.02.003