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LC–MS/MS determination and pharmacokinetic study of bergenin, the main bioactive component of Bergenia purpurascens after oral administration in rats
Bergenin, a C-glucoside of 4-O-methyl gallic acid from Bergenia purpurascens, is a naturally antitussive and expectorant agent. A rapid and sensitive liquid chromatography tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the determination of the active component—bergen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760982/ https://www.ncbi.nlm.nih.gov/pubmed/29403822 http://dx.doi.org/10.1016/j.jpha.2013.01.005 |