Application of UPLC–MS/MS for separation and quantification of 3α-Hydroxy Tibolone and comparative bioavailability of two Tibolone formulations in healthy volunteers

A novel, fast, sensitive and robust method based on ultra-performance liquid chromatography coupled to atmospheric pressure electrospray ionization tandem mass spectrometry (UPLC–ESI-MS/MS) has been developed to separate two Tibolone stereoisomers i.e., 3α-Hydroxy Tibolone and 3β-Hydroxy Tibolone an...

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Detalles Bibliográficos
Autores principales: Shinde, Vijay P., Pudage, Ashutosh, Jangid, Arvind, Mistri, Hiren, Patel, P.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760983/
https://www.ncbi.nlm.nih.gov/pubmed/29403827
http://dx.doi.org/10.1016/j.jpha.2013.02.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760983/
https://www.ncbi.nlm.nih.gov/pubmed/29403827
http://dx.doi.org/10.1016/j.jpha.2013.02.006

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