Copper interactions with DNA of chromatin and its role in neurodegenerative disorders

In this study, we have demonstrated the conformational changes to DNA induced by abnormal interactions of copper using circular dichroism, in combination with UV-absorbance and fluorescence spectroscopy. Results confirm that binding of copper to bases of DNA in chromatin is concentration dependent....

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Detalles Bibliográficos
Autores principales: Govindaraju, M., Shekar, H.S., Sateesha, S.B., Vasudeva Raju, P., Sambasiva Rao, K.R., Rao, K.S.J., Rajamma, A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760996/
https://www.ncbi.nlm.nih.gov/pubmed/29403839
http://dx.doi.org/10.1016/j.jpha.2013.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760996/
https://www.ncbi.nlm.nih.gov/pubmed/29403839
http://dx.doi.org/10.1016/j.jpha.2013.03.003

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