Simultaneous determination of asenapine and valproic acid in human plasma using LC–MS/MS: Application of the method to support pharmacokinetic study

Combination of asenapine with valproic acid received regulatory approval for acute treatment of schizophrenia and maniac episodes of bipolar disorders. A simple LC–MS/MS method was developed and validated for simultaneous quantification of asenapine and valproic acid in human plasma. Internal standa...

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Detalles Bibliográficos
Autores principales: Reddy, Ambavaram Vijaya Bhaskar, Venugopal, Nandigam, Madhavi, Gajulapalle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761000/
https://www.ncbi.nlm.nih.gov/pubmed/29403845
http://dx.doi.org/10.1016/j.jpha.2013.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761000/
https://www.ncbi.nlm.nih.gov/pubmed/29403845
http://dx.doi.org/10.1016/j.jpha.2013.04.008

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