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Optimization and validation of a fast RP–HPLC method for the determination of dobutamine in rat plasma: Pharmacokinetic studies in healthy rat subjects

A novel isocratic reverse phase high performance liquid chromatography (RP–HPLC) with photo diode array (PDA) detection method for the determination of dobutamine (DBT) in rat plasma was developed and validated after optimization of various chromatographic conditions and other experimental parameter...

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Detalles Bibliográficos
Autores principales: Thippani, Ramesh, Pothuraju, Nageswara Rao, Ramisetti, Nageswara Rao, Shaik, Saida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761010/
https://www.ncbi.nlm.nih.gov/pubmed/29403851
http://dx.doi.org/10.1016/j.jpha.2013.07.003