Development of a sensitive and rapid method for quantitation of (S)-(−)- and (R)-(+)-metoprolol in human plasma by chiral LC–ESI–MS/MS

A selective, sensitive and high throughput liquid chromatography-tandem mass spectrometry (LC–ESI–MS/MS) method has been developed for separation and quantification of metoprolol enantiomers on a chiral Lux Amylose-2 (250 mm×4.6 mm, 5 μm) column. Solid phase extraction of (S)-(−)- and (R)-(+)-metopr...

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Detalles Bibliográficos
Autores principales: Sharma, Primal, Contractor, Pritesh, Guttikar, Swati, Patel, Daxesh P., Shrivastav, Pranav S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761053/
https://www.ncbi.nlm.nih.gov/pubmed/29403869
http://dx.doi.org/10.1016/j.jpha.2013.02.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761053/
https://www.ncbi.nlm.nih.gov/pubmed/29403869
http://dx.doi.org/10.1016/j.jpha.2013.02.008

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