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Improved simultaneous quantitation of candesartan and hydrochlorthiazide in human plasma by UPLC–MS/MS and its application in bioequivalence studies

A validated ultra-performance liquid chromatography mass spectrometric method (UPLC–MS/MS) was used for the simultaneous quantitation of candesartan (CN) and hydrochlorothiazide (HCT) in human plasma. The analysis was performed on UPLC–MS/MS system using turbo ion spray interface. Negative ions were...

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Detalles Bibliográficos
Autores principales: Singh, Bhupinder, Lokhandae, Rama S., Dwivedi, Ashish, Sharma, Sandeep, Dubey, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761088/
https://www.ncbi.nlm.nih.gov/pubmed/29403876
http://dx.doi.org/10.1016/j.jpha.2013.05.003