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Placental hypoxia-regulating network in relation to birth weight and ponderal index: the ENVIRONAGE Birth Cohort Study

BACKGROUND: HIF1α, miR-210 and its downstream targets ISCU, COX-10, RAD52 and PTEN are all part of the placental hypoxia-responsive network. Tight regulation of this network is required to prevent development of maternal–fetal complications such as fetal growth restriction. HIF1α expression is incre...

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Detalles Bibliográficos
Autores principales: Vrijens, Karen, Tsamou, Maria, Madhloum, Narjes, Gyselaers, Wilfried, Nawrot, Tim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761191/
https://www.ncbi.nlm.nih.gov/pubmed/29316938
http://dx.doi.org/10.1186/s12967-017-1375-5