TPF induction chemotherapy increases PD-L1 expression in tumour cells and immune cells in head and neck squamous cell carcinoma

BACKGROUND: Antiprogrammed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) therapies have demonstrated promising activity in advanced head and neck squamous cell carcinoma (HNSCC), with overall response rates of approximately 20% in unselected populations and survival benefit. Whether induc...

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Detalles Bibliográficos
Autores principales: Leduc, Charlotte, Adam, Julien, Louvet, Emilie, Sourisseau, Tony, Dorvault, Nicolas, Bernard, Marine, Maingot, Elodie, Faivre, Laura, Cassin-Kuo, Mei-Shiue, Boissier, Emilie, Dessoliers, Marie-Charlotte, Robin, Angélique, Casiraghi, Odile, Even, Caroline, Temam, Stéphane, Olaussen, Ken A, Soria, Jean-Charles, Postel-Vinay, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761289/
https://www.ncbi.nlm.nih.gov/pubmed/29344407
http://dx.doi.org/10.1136/esmoopen-2017-000257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761289/
https://www.ncbi.nlm.nih.gov/pubmed/29344407
http://dx.doi.org/10.1136/esmoopen-2017-000257

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