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Development of an LC−MS/MS method for determination of 2-oxo-clopidogrel in human plasma
A sensitive and selective liquid chromatography–tandem mass spectrometric (LC−MS/MS) method was established to determine 2-oxo-clopidogrel, a crucial intermediate metabolite in human plasma. A chromatographic separation was performed on a Sapphire C(18) column following a liquid–liquid extraction sa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Xi'an Jiaotong University
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761481/ https://www.ncbi.nlm.nih.gov/pubmed/29403910 http://dx.doi.org/10.1016/j.jpha.2014.07.004 |