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LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine

In the present study, comprehensive stress testing of amlodipine (AM) was carried out according to International Conference on Harmonization (ICH) Q1A(R2) guideline. AM was subjected to acidic, neutral and alkaline hydrolysis, oxidation, photolysis and thermal stress conditions. The drug showed inst...

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Detalles Bibliográficos
Autores principales: Tiwari, Ravi N., Shah, Nishit, Bhalani, Vikas, Mahajan, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761482/
https://www.ncbi.nlm.nih.gov/pubmed/29403913
http://dx.doi.org/10.1016/j.jpha.2014.07.005