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LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine
In the present study, comprehensive stress testing of amlodipine (AM) was carried out according to International Conference on Harmonization (ICH) Q1A(R2) guideline. AM was subjected to acidic, neutral and alkaline hydrolysis, oxidation, photolysis and thermal stress conditions. The drug showed inst...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Xi'an Jiaotong University
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761482/ https://www.ncbi.nlm.nih.gov/pubmed/29403913 http://dx.doi.org/10.1016/j.jpha.2014.07.005 |