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The Absence of Laminin α4 in Male Mice Results in Enhanced Energy Expenditure and Increased Beige Subcutaneous Adipose Tissue

Laminin α4 (LAMA4) is located in the extracellular basement membrane that surrounds each individual adipocyte. Here we show that LAMA4 null (Lama4(−/−)) mice exhibit significantly higher energy expenditure (EE) relative to wild-type (WT) mice at room temperature and when exposed to a cold challenge,...

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Detalles Bibliográficos
Autores principales: Vaicik, Marcella K., Blagajcevic, Alen, Ye, Honggang, Morse, Mallory C., Yang, Feipeng, Goddi, Anna, Brey, Eric M., Cohen, Ronald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761598/
https://www.ncbi.nlm.nih.gov/pubmed/28973559
http://dx.doi.org/10.1210/en.2017-00186