Cargando…

Metabolic regulation of the PMCA: Role in cell death and survival()

The plasma membrane Ca(2+)-ATPase (PMCA) is a ubiquitously expressed, ATP-driven Ca(2+) pump that is critical for maintaining low resting cytosolic Ca(2+) ([Ca(2+)](i)) in all eukaryotic cells. Since cytotoxic Ca(2+) overload has such a central role in cell death, the PMCA represents an essential “l...

Descripción completa

Detalles Bibliográficos
Autor principal: Bruce, Jason I.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761718/
https://www.ncbi.nlm.nih.gov/pubmed/28625348
http://dx.doi.org/10.1016/j.ceca.2017.06.001