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miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels

Pathophysiological mechanisms underlying pain associated with cancer are poorly understood. microRNAs (miRNAs) are a class of noncoding RNAs with emerging functional importance in chronic pain. In a genome-wide screen for miRNAs regulated in dorsal root ganglia (DRG) neurons in a mouse model of bone...

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Detalles Bibliográficos
Autores principales: Gandla, Jagadeesh, Lomada, Santosh Kumar, Lu, Jianning, Kuner, Rohini, Bali, Kiran Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761751/
https://www.ncbi.nlm.nih.gov/pubmed/28614186
http://dx.doi.org/10.1097/j.pain.0000000000000971