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Agent-based modeling of the interaction between CD8(+) T cells and Beta cells in type 1 diabetes
We propose an agent-based model for the simulation of the autoimmune response in T1D. The model incorporates cell behavior from various rules derived from the current literature and is implemented on a high-performance computing system, which enables the simulation of a significant portion of the is...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761894/ https://www.ncbi.nlm.nih.gov/pubmed/29320541 http://dx.doi.org/10.1371/journal.pone.0190349 |