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Agent-based modeling of the interaction between CD8(+) T cells and Beta cells in type 1 diabetes

We propose an agent-based model for the simulation of the autoimmune response in T1D. The model incorporates cell behavior from various rules derived from the current literature and is implemented on a high-performance computing system, which enables the simulation of a significant portion of the is...

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Detalles Bibliográficos
Autores principales: Ozturk, Mustafa Cagdas, Xu, Qian, Cinar, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761894/
https://www.ncbi.nlm.nih.gov/pubmed/29320541
http://dx.doi.org/10.1371/journal.pone.0190349