Distinct expression of functionally glycosylated alpha-dystroglycan in muscle and non-muscle tissues of FKRP mutant mice

The glycosylation of alpha-dystroglycan (α-DG) is crucial in maintaining muscle cell membrane integrity. Dystroglycanopathies are identified by the loss of this glycosylation leading to a breakdown of muscle cell membrane integrity and eventual degeneration. However, a small portion of fibers expres...

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Detalles Bibliográficos
Autores principales: Blaeser, Anthony, Awano, Hiroyuki, Lu, Pei, Lu, Qi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761899/
https://www.ncbi.nlm.nih.gov/pubmed/29320543
http://dx.doi.org/10.1371/journal.pone.0191016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761899/
https://www.ncbi.nlm.nih.gov/pubmed/29320543
http://dx.doi.org/10.1371/journal.pone.0191016

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