Cryo-EM structure of the lysosomal Ca(2+)-permeable channel TRPML3

The modulation of ion channel activity by lipids is increasingly recognized as a fundamental component of cellular signaling. The mucolipin transient receptor potential (TRPML) channel family belongs to the TRP superfamily(1,2) and is composed of three members, TRPML1-3. TRPMLs are the major Ca(2+)-...

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Detalles Bibliográficos
Autores principales: Hirschi, Marscha, Herzik, Mark A., Wie, Jinhong, Suo, Yang, Borschel, William F., Ren, Dejian, Lander, Gabriel C., Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762132/
https://www.ncbi.nlm.nih.gov/pubmed/29019979
http://dx.doi.org/10.1038/nature24055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762132/
https://www.ncbi.nlm.nih.gov/pubmed/29019979
http://dx.doi.org/10.1038/nature24055

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