Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity

Despite extensive scrutiny of the myosin superfamily, the lack of high-resolution structures of actin-bound states has prevented a complete description of its mechanochemical cycle and limited insight into how sequence and structural diversification of the motor domain gives rise to specialized func...

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Detalles Bibliográficos
Autores principales: Gurel, Pinar S, Kim, Laura Y, Ruijgrok, Paul V, Omabegho, Tosan, Bryant, Zev, Alushin, Gregory M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762158/
https://www.ncbi.nlm.nih.gov/pubmed/29199952
http://dx.doi.org/10.7554/eLife.31125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762158/
https://www.ncbi.nlm.nih.gov/pubmed/29199952
http://dx.doi.org/10.7554/eLife.31125

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