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Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity
Despite extensive scrutiny of the myosin superfamily, the lack of high-resolution structures of actin-bound states has prevented a complete description of its mechanochemical cycle and limited insight into how sequence and structural diversification of the motor domain gives rise to specialized func...
Autores principales: | Gurel, Pinar S, Kim, Laura Y, Ruijgrok, Paul V, Omabegho, Tosan, Bryant, Zev, Alushin, Gregory M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762158/ https://www.ncbi.nlm.nih.gov/pubmed/29199952 http://dx.doi.org/10.7554/eLife.31125 |
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