The kinetics of pre-mRNA splicing in the Drosophila genome and the influence of gene architecture

Production of most eukaryotic mRNAs requires splicing of introns from pre-mRNA. The splicing reaction requires definition of splice sites, which are initially recognized in either intron-spanning (‘intron definition’) or exon-spanning (‘exon definition’) pairs. To understand how exon and intron leng...

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Detalles Bibliográficos
Autores principales: Pai, Athma A, Henriques, Telmo, McCue, Kayla, Burkholder, Adam, Adelman, Karen, Burge, Christopher B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762160/
https://www.ncbi.nlm.nih.gov/pubmed/29280736
http://dx.doi.org/10.7554/eLife.32537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762160/
https://www.ncbi.nlm.nih.gov/pubmed/29280736
http://dx.doi.org/10.7554/eLife.32537

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