Isolation and characterization of a degradation product in leflunomide and a validated selective stability-indicating HPLC–UV method for their quantification

Leflunomide (LLM) is subjected to forced degradation under conditions of hydrolysis, oxidation, dry heat, and photolysis as recommended by International Conference on Harmonization guideline Q1A(R2). In total, four degradation products (I–IV) were formed under different conditions. Products I, II an...

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Detalles Bibliográficos
Autores principales: Saini, Balraj, Bansal, Gulshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762194/
https://www.ncbi.nlm.nih.gov/pubmed/29403933
http://dx.doi.org/10.1016/j.jpha.2014.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762194/
https://www.ncbi.nlm.nih.gov/pubmed/29403933
http://dx.doi.org/10.1016/j.jpha.2014.10.003

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