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Liquid chromatography–tandem mass spectrometry method for the estimation of adefovir in human plasma: Application to a pharmacokinetic study

An analytical method based on solid phase extraction was developed and validated for analysis of adefovir in human plasma. Adefovir-d(4) was used as an internal standard and Synergi MAX RP80A (150 mm×4.6 mm, 4 µm) column provided the desired chromatographic separation of compounds followed by detect...

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Detalles Bibliográficos
Autores principales: Goswami, Dipanjan, Gurule, Sanjay, Saha, Arabinda, Vats, Poonam, Khuroo, Arshad, Monif, Tausif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762195/
https://www.ncbi.nlm.nih.gov/pubmed/29403931
http://dx.doi.org/10.1016/j.jpha.2014.08.002