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Simultaneous determination of four Sudan dyes in rat blood by UFLC–MS/MS and its application to a pharmacokinetic study in rats()

A rapid and sensitive method based on ultrafast liquid chromatography–tandem mass spectrometry was developed and validated for simultaneous determination of Sudan I, Sudan II, Sudan III, and Sudan IV levels in rat whole blood. Cleanert C18 mixed-mode polymeric sorbent was used for effective solid-ph...

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Detalles Bibliográficos
Autores principales: Zhu, Hao, Chen, Yijun, Huang, Changshun, Han, Yangyang, Zhang, Yiwei, Xie, Shucan, Chen, Xiaohong, Jin, Micong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762213/
https://www.ncbi.nlm.nih.gov/pubmed/29403937
http://dx.doi.org/10.1016/j.jpha.2015.03.001