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Multiple responses optimization in the development of a headspace gas chromatography method for the determination of residual solvents in pharmaceuticals()
An efficient generic static headspace gas chromatography (HSGC) method was developed, optimized and validated for the routine determination of several residual solvents (RS) in drug substance, using a strategy with two sets of calibration. Dimethylsulfoxide (DMSO) was selected as the sample diluent...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762238/ https://www.ncbi.nlm.nih.gov/pubmed/29403943 http://dx.doi.org/10.1016/j.jpha.2015.02.004 |