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Determination of atractylon in rat plasma by a GC–MS method and its application to a pharmacokinetic study()

A sensitive and selective method based on gas chromatography hyphenated to mass spectrometry (GC–MS) was developed and validated for the determination of atractylon in rat plasma. Plasma samples were processed by liquid–liquid extraction with ethyl acetate-n-hexane (1:1, v/v) using acetophenone as a...

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Detalles Bibliográficos
Autores principales: Yan, Han, Sun, Yuanyuan, Ma, Yuying, Ji, Bin, Hou, Xiaohong, Yu, Zhiguo, Zhao, Yunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762239/
https://www.ncbi.nlm.nih.gov/pubmed/29403946
http://dx.doi.org/10.1016/j.jpha.2015.03.002