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Synthetically Lethal Nanoparticles for Treatment of Endometrial Cancer

Uterine serous carcinoma, one of the most aggressive types of endometrial cancer, is characterized by poor outcomes and mutations in the tumor suppressor p53. Our objective was to engender synthetic lethality to paclitaxel, the frontline treatment for endometrial cancer, in tumors with mutant p53 an...

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Detalles Bibliográficos
Autores principales: Ebeid, Kareem, Meng, Xiangbing, Thiel, Kristina W, Do, Anh-Vu, Geary, Sean M, Morris, Angie S, Pham, Erica L, Wongrakpanich, Amaraporn, Chhonker, Yashpal S, Murry, Daryl J, Leslie, Kimberly K, Salem, Aliasger K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762267/
https://www.ncbi.nlm.nih.gov/pubmed/29203914
http://dx.doi.org/10.1038/s41565-017-0009-7