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The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme
Glioblastoma multiforme (GBM) is the deadliest brain tumor. State-of-art GBM therapy often fails to ensure control of a disease characterized by high frequency of recurrences and progression. In search for novel therapeutic approaches, we assayed the effect of compounds from a cancer drug library on...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762281/ https://www.ncbi.nlm.nih.gov/pubmed/29340013 http://dx.doi.org/10.18632/oncotarget.22500 |