The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme

Glioblastoma multiforme (GBM) is the deadliest brain tumor. State-of-art GBM therapy often fails to ensure control of a disease characterized by high frequency of recurrences and progression. In search for novel therapeutic approaches, we assayed the effect of compounds from a cancer drug library on...

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Detalles Bibliográficos
Autores principales: Abbruzzese, Claudia, Catalogna, Giada, Gallo, Enzo, di Martino, Simona, Mileo, Anna M., Carosi, Mariantonia, Dattilo, Vincenzo, Schenone, Silvia, Musumeci, Francesca, Lavia, Patrizia, Perrotti, Nicola, Amato, Rosario, Paggi, Marco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762281/
https://www.ncbi.nlm.nih.gov/pubmed/29340013
http://dx.doi.org/10.18632/oncotarget.22500

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