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Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins

The combination of radiotherapy and pharmacological inhibition of cellular signal transduction pathways offers promising strategies for enhanced cancer cell inactivation. However, the molecular effects of kinase inhibitors especially on DNA damage detection and repair after X-irradiation have to be...

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Detalles Bibliográficos
Autores principales: Gleißner, Lisa, Kwiatkowski, Marcel, Myllynen, Laura, Steffen, Pascal, Petersen, Cordula, Rothkamm, Kai, Schlüter, Hartmut, Kriegs, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762299/
https://www.ncbi.nlm.nih.gov/pubmed/29340031
http://dx.doi.org/10.18632/oncotarget.22424