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Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins
The combination of radiotherapy and pharmacological inhibition of cellular signal transduction pathways offers promising strategies for enhanced cancer cell inactivation. However, the molecular effects of kinase inhibitors especially on DNA damage detection and repair after X-irradiation have to be...
Autores principales: | Gleißner, Lisa, Kwiatkowski, Marcel, Myllynen, Laura, Steffen, Pascal, Petersen, Cordula, Rothkamm, Kai, Schlüter, Hartmut, Kriegs, Malte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762299/ https://www.ncbi.nlm.nih.gov/pubmed/29340031 http://dx.doi.org/10.18632/oncotarget.22424 |
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