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Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals

Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy that is often resistant to therapy. Nowadays, chemotherapy is still one of the main methods for the treatment of ESCC. However, the multidrug resistance (MDR)-mediated chemotherapy resistance is one of the leading causes of death....

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Detalles Bibliográficos
Autores principales: Zhou, Pengjun, Zhang, Rong, Wang, Ying, Xu, Dandan, Zhang, Li, Qin, Jinhong, Su, Guifeng, Feng, Yue, Chen, Hongce, You, Siyuan, Rui, Wen, Liu, Huizhong, Chen, Suhong, Chen, Hongyuan, Wang, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762312/
https://www.ncbi.nlm.nih.gov/pubmed/29340044
http://dx.doi.org/10.18632/oncotarget.22676