Temozolomide encapsulated and folic acid decorated chitosan nanoparticles for lung tumor targeting: improving therapeutic efficacy both in vitro and in vivo

Folic acid-conjugated temozolomide (TMZ)-loaded chitosan nanoparticles (CS-TMZ-FLA-NP) were developed to target lung cancer in the anticipation that folic acid would increase the affinity of nanoparticles for cancer cells. CS-TMZ-FLA-NP showed the highest anti-proliferative effect on the lung cancer...

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Detalles Bibliográficos
Autores principales: Li, Kaidi, Liang, Naixin, Yang, Huaxia, Liu, Hongsheng, Li, Shanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762324/
https://www.ncbi.nlm.nih.gov/pubmed/29340056
http://dx.doi.org/10.18632/oncotarget.22791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762324/
https://www.ncbi.nlm.nih.gov/pubmed/29340056
http://dx.doi.org/10.18632/oncotarget.22791

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