A molecular signature of dormancy in CD34(+)CD38(-) acute myeloid leukaemia cells

Dormant leukaemia initiating cells in the bone marrow niche are a crucial therapeutic target for total eradication of acute myeloid leukaemia. To study this cellular subset we created and validated an in vitro model employing the cell line TF-1a, treated with Transforming Growth Factor β1 (TGFβ1) an...

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Detalles Bibliográficos
Autores principales: Al-Asadi, Mazin Gh., Brindle, Grace, Castellanos, Marcos, May, Sean T., Mills, Ken I., Russell, Nigel H., Seedhouse, Claire H., Pallis, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762331/
https://www.ncbi.nlm.nih.gov/pubmed/29340063
http://dx.doi.org/10.18632/oncotarget.22808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762331/
https://www.ncbi.nlm.nih.gov/pubmed/29340063
http://dx.doi.org/10.18632/oncotarget.22808

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