Comparison of reversed-phase enantioselective HPLC methods for determining the enantiomeric purity of (S)-omeprazole in the presence of its related substances()

A simple analytical high-performance liquid chromatography (HPLC) method was applied for the enantiomeric excess determination of esomeprazole ((S)-OME), the enantiopure active ingredient contained in drug products, in the presence of its potential organic impurities A-E. The enantioselective separa...

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Detalles Bibliográficos
Autores principales: Gallinella, Bruno, Ferretti, Rosella, Zanitti, Leo, Sestili, Isabella, Mosca, Antonina, Cirilli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762455/
https://www.ncbi.nlm.nih.gov/pubmed/29403973
http://dx.doi.org/10.1016/j.jpha.2015.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762455/
https://www.ncbi.nlm.nih.gov/pubmed/29403973
http://dx.doi.org/10.1016/j.jpha.2015.11.001

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