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Simultaneous determination of doxorubicin and its dipeptide prodrug in mice plasma by HPLC with fluorescence detection()

A simple and sensitive high performance liquid chromatography with fluorescence detection (HPLC–FD) has been developed for simultaneous quantification of doxorubicin (DOX) and its dipeptide conjugate prodrug (PDOX) in mice plasma. The chromatographic separation was carried out on an Amethyst C(18)–H...

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Detalles Bibliográficos
Autores principales: Han, Jing, Zhang, Jue, Zhao, Haiyan, Li, Yan, Chen, Zilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762492/
https://www.ncbi.nlm.nih.gov/pubmed/29403982
http://dx.doi.org/10.1016/j.jpha.2015.12.005