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Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts
The invasion of activated fibroblasts is a key mechanism of tissue fibrosis pathology. The recognition and uptake of apoptotic cells can induce the anti-fibrogenic programming of macrophages. We demonstrate that after interacting with apoptotic cells, macrophages secrete bioactive molecules that ant...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762511/ https://www.ncbi.nlm.nih.gov/pubmed/29348826 http://dx.doi.org/10.18632/oncotarget.22737 |