Cargando…

Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts

The invasion of activated fibroblasts is a key mechanism of tissue fibrosis pathology. The recognition and uptake of apoptotic cells can induce the anti-fibrogenic programming of macrophages. We demonstrate that after interacting with apoptotic cells, macrophages secrete bioactive molecules that ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Yong-Bae, Yoon, Young-So, Choi, Youn-Hee, Park, Eun-Mi, Kang, Jihee Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762511/
https://www.ncbi.nlm.nih.gov/pubmed/29348826
http://dx.doi.org/10.18632/oncotarget.22737