Simultaneous quantification of DNA damage and mitochondrial copy number by long-run DNA-damage quantification (LORD-Q)

DNA damage and changes in the mitochondrial DNA content have been implicated in ageing and cancer development. To prevent genomic instability and tumorigenesis, cells must maintain the integrity of their nuclear and mitochondrial DNA. Advances in the research of DNA damage protection and genomic sta...

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Detalles Bibliográficos
Autores principales: Dannenmann, Benjamin, Lehle, Simon, Lorscheid, Sebastian, Huber, Stephan M., Essmann, Frank, Schulze-Osthoff, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762520/
https://www.ncbi.nlm.nih.gov/pubmed/29348835
http://dx.doi.org/10.18632/oncotarget.20112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762520/
https://www.ncbi.nlm.nih.gov/pubmed/29348835
http://dx.doi.org/10.18632/oncotarget.20112

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