Activation of AMPK by OSU53 protects spinal cord neurons from oxidative stress

The present study tested the potential effect of OSU53, a novel AMPK activator, against hydrogen peroxide (H2O2)-induced spinal cord neuron damages. Treatment with OSU53 attenuated H2O2-induced death and apoptosis of primary murine spinal cord neurons. OSU53 activated AMPK signaling, which is requir...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Wu, Liang, Zhang, Yiming, Gu, Huijie, Huang, Zhongyue, Zhou, Kaifeng, Yin, Xiaofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762526/
https://www.ncbi.nlm.nih.gov/pubmed/29348841
http://dx.doi.org/10.18632/oncotarget.22055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762526/
https://www.ncbi.nlm.nih.gov/pubmed/29348841
http://dx.doi.org/10.18632/oncotarget.22055

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