Novel indazole-based small compounds enhance TRAIL-induced apoptosis by inhibiting the MKK7-TIPRL interaction in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most malignant tumors. Although various treatments, such as surgery and chemotherapy, have been developed, a novel alternative therapeutic approach for HCC therapy is urgently needed. Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is a pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Ji-Yong, Lee, Jeong-Ju, Gu, Sujin, Jung, Myoung Eun, Cho, Hyun-Soo, Lim, Jung Hwa, Jun, Soo Young, Ahn, Jun-Ho, Min, Ju-Sik, Choi, Min-Hyuk, Jeon, Su-Jin, Lee, Yong-Jae, Go, Areum, Heo, Yun-Jeong, Jung, Cho-Rok, Choi, Gildon, Lee, Kwangho, Jeon, Moon-Kook, Kim, Nam-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762535/
https://www.ncbi.nlm.nih.gov/pubmed/29348850
http://dx.doi.org/10.18632/oncotarget.22614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762535/
https://www.ncbi.nlm.nih.gov/pubmed/29348850
http://dx.doi.org/10.18632/oncotarget.22614

Ejemplares similares